A retrospective observational case series of low flow veno-venous extracorporeal carbon dioxide removal use in patients with respiratory failure

Moss C.E., Galtrey E., Gillon S., Langrish C., Meadows C., Wyncoll D., Ioannou N., Camporota L., Tricklebank S., Daly K., Evans S., Ong D., Sanderson B., Waldie J., Dando R., Elliott-Hammond C., Lozinski M., Nichols H., Barrett N.
Department of Critical Care, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom

Poster presentation from the EuroELSO 2015 4th International Congress.

Summary

Dr. Barrett and colleagues present a retrospective, observational case series of using extracorporeal carbon dioxide removal (ECCO2R) in patients with acute respiratory failure. Fourteen patients were included in the report and divided into two subgroups: exacerbated COPD (n=5) and ARDS with persisting hypercapnia despite lung protective ventilation (n=9). Clinical effects of ECCO2R included statistically significant improvements on pH and pCO2 in both groups. In the COPD group, 2/3 patients avoided intubation, and 2/2 patients were successfully extubated early. In the ARDS group, a trend towards reduction in driving pressure was achieved (through reduction in inspiratory pressure and elevation of PEEP). The authors concluded, “Our retrospective, observational series of ECCO2R shows that ECCO2R is a promising technique for the management of patients with COPD and that ECCO2R can be used to achieve lung protective goals in patients with ARDS, supporting the existing literature.”

View the poster here (PDF)

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